| 67 | === User Mode Interactions === |
| 68 | All files are shipped with no file access code security for reading, and as such they can be read by all users if they are granted access to Fileman and don't have Kernel Part III security turned on. If Kernel Part III security is turned on, you will need to grant users access to files 176.001 through 176.006. If you don't know what Part III security is, then you don't have it. |
| 69 | |
| 70 | ==== Concepts ==== |
| 71 | Users can query the Concepts file by typing the concept name (usually a drug generic name or brand name) or a drug code (such as a VUID). Here are a couple of examples: |
| 72 | |
| 73 | Search for all entries that have the word PROZAC in them: |
| 74 | {{{ |
| 75 | Select RXNORM CONCEPT NAMES AND SOURCES RXCUI: PROZAC |
| 76 | 1 PROZAC 58827 MSH PEN D005473 Prozac |
| 77 | 2 PROZAC 58827 RXNORM TMSY 58827 PROzac |
| 78 | 3 PROZAC 58827 RXNORM BN 58827 Prozac |
| 79 | 4 PROZAC 10 MG (FLUOXETINE HYDRO 205535 RXNORM SY 205535 |
| 80 | Prozac 10 MG (fluoxetine hydrochloride 11.2 MG) Oral Capsule |
| 81 | 5 PROZAC 10 MG (FLUOXETINE HYDRO 205535 RXNORM TMSY 205535 |
| 82 | PROzac 10 MG (FLUoxetine hydrochloride 11.2 MG) Oral Capsule |
| 83 | }}} |
| 84 | |
| 85 | Search for the VUID for Prozac after we obtain it from the NDF: |
| 86 | {{{ |
| 87 | OUTPUT FROM WHAT FILE: RXNORM CONCEPT NAMES AND SOURCES// 50.68 VA PRODUCT |
| 88 | (23779 entries) |
| 89 | Select VA PRODUCT NAME: FLUOXETINE |
| 90 | 1 FLUOXETINE HCL 10MG CAP |
| 91 | 2 FLUOXETINE HCL 10MG CAP,UD |
| 92 | 3 FLUOXETINE HCL 10MG TAB |
| 93 | 4 FLUOXETINE HCL 20MG CAP |
| 94 | 5 FLUOXETINE HCL 20MG CAP,UD |
| 95 | Press <RETURN> to see more, '^' to exit this list, OR |
| 96 | CHOOSE 1-5: 4 FLUOXETINE HCL 20MG CAP |
| 97 | ANOTHER ONE: |
| 98 | STANDARD CAPTIONED OUTPUT? Yes// (Yes) |
| 99 | Include COMPUTED fields: (N/Y/R/B): NO// - No record number (IEN), no Computed |
| 100 | Fields |
| 101 | DISPLAY AUDIT TRAIL? No// NO |
| 102 | |
| 103 | NAME: FLUOXETINE HCL 20MG CAP VA GENERIC NAME: FLUOXETINE |
| 104 | DOSAGE FORM: CAP,ORAL STRENGTH: 20 |
| 105 | UNITS: MG |
| 106 | NATIONAL FORMULARY NAME: FLUOXETINE CAP,ORAL |
| 107 | VA PRINT NAME: FLUOXETINE HCL 20MG CAP |
| 108 | VA PRODUCT IDENTIFIER: F0049 TRANSMIT TO CMOP: YES |
| 109 | VA DISPENSE UNIT: CAP |
| 110 | ACTIVE INGREDIENTS: FLUOXETINE HYDROCHLORIDE |
| 111 | STRENGTH: 20 UNITS: MG |
| 112 | PRIMARY VA DRUG CLASS: CN609 NATIONAL FORMULARY INDICATOR: YES |
| 113 | CS FEDERAL SCHEDULE: Unscheduled SINGLE/MULTI SOURCE PRODUCT: Multisource |
| 114 | DSS NUMBER: 1 OVERRIDE DF DOSE CHK EXCLUSION: NO |
| 115 | CREATE DEFAULT POSSIBLE DOSAGE: YES |
| 116 | FDA MED GUIDE: Fluoxetine_Cap_(Generic)_(2009).pdf |
| 117 | SERVICE CODE: 608147 |
| 118 | EFFECTIVE DATE/TIME: MAR 10, 2005 STATUS: ACTIVE |
| 119 | VUID: 4008621 MASTER ENTRY FOR VUID: YES |
| 120 | |
| 121 | |
| 122 | |
| 123 | Select VA PRODUCT NAME: |
| 124 | |
| 125 | |
| 126 | |
| 127 | |
| 128 | Select OPTION: INQUIRE TO FILE ENTRIES |
| 129 | |
| 130 | |
| 131 | |
| 132 | OUTPUT FROM WHAT FILE: VA PRODUCT// 176.001 RXNORM CONCEPT NAMES AND SOURCES |
| 133 | (687143 entries) |
| 134 | Select RXNORM CONCEPT NAMES AND SOURCES RXCUI: 4008621 |
| 135 | 1 4008621 310385 VANDF CD 4008621 FLUOXETINE HCL 20MG CA |
| 136 | P |
| 137 | 2 4008621 310385 VANDF AB 4008621 FLUOXETINE HCL 20MG CA |
| 138 | P |
| 139 | CHOOSE 1-2: 1 310385 VANDF CD 4008621 FLUOXETINE HCL 20MG CAP |
| 140 | ANOTHER ONE: |
| 141 | STANDARD CAPTIONED OUTPUT? Yes// (Yes) |
| 142 | Include COMPUTED fields: (N/Y/R/B): NO// - No record number (IEN), no Computed |
| 143 | Fields |
| 144 | |
| 145 | RXCUI: 310385 LAT: ENG |
| 146 | RXAUI: 1424227 SAB: VANDF |
| 147 | TTY: CD CODE: 4008621 |
| 148 | STR: FLUOXETINE HCL 20MG CAP SUPPRESS: N |
| 149 | |
| 150 | }}} |
| 151 | |
| 152 | ==== Atoms ==== |
| 153 | To search the Atoms file, chose file 176.002. You can search by the type of Atom or the Atom itself. The most useful thing to search here are NDC numbers. Here's a search for a Prozac NDC. |
| 154 | |
| 155 | {{{ |
| 156 | Select RXNORM SIMPLE CONCEPT AND ATOM ATTRIBUTES ATN: 00777310502 NDC RXNOR |
| 157 | M 00777310502 |
| 158 | ANOTHER ONE: |
| 159 | STANDARD CAPTIONED OUTPUT? Yes// (Yes) |
| 160 | Include COMPUTED fields: (N/Y/R/B): NO// - No record number (IEN), no Computed |
| 161 | Fields |
| 162 | |
| 163 | ATN: NDC RXAUI: 787787 |
| 164 | STYPE: AUI CODE: 104849 |
| 165 | RXCUI: 104849 SAB: RXNORM |
| 166 | ATV: 00777310502 SUPPRESS: N |
| 167 | CVF: 4096 |
| 168 | }}} |
| 169 | |
| 170 | You can also enter an !RxNorm concept code to get all available atoms about a drug. Using the RXCUI we just obtained above, we can get an exhaustive list of everything about it: |
| 171 | |
| 172 | {{{ |
| 173 | OUTPUT FROM WHAT FILE: RXNORM SIMPLE CONCEPT AND ATOM ATTRIBUTES// |
| 174 | |
| 175 | Select RXNORM SIMPLE CONCEPT AND ATOM ATTRIBUTES ATN: 104849 |
| 176 | 1 104849 NST MTHFDA 20 MG |
| 177 | 2 104849 NDC MTHFDA 054868-0511-*1 |
| 178 | 3 104849 NDC MTHFDA 053002-1016-*0 |
| 179 | 4 104849 DRT MTHFDA ORAL |
| 180 | 5 104849 NDC RXNORM 00777310502 |
| 181 | Press <RETURN> to see more, '^' to exit this list, OR |
| 182 | CHOOSE 1-5: |
| 183 | 6 104849 NDC MTHFDA 016590-*843-90 |
| 184 | 7 104849 DDF MTHFDA CAPSULE |
| 185 | 8 104849 NDC MTHFDA 000002-3105-14 |
| 186 | 9 104849 NDC MTHFDA 051655-*390-25 |
| 187 | 10 104849 NDC MTHFDA 054868-0511-*5 |
| 188 | Press <RETURN> to see more, '^' to exit this list, OR |
| 189 | CHOOSE 1-10: |
| 190 | 11 104849 DDF MTHFDA CAPSULE, GELATIN COATED |
| 191 | 12 104849 MARKETING_STATUS MTHSPL active |
| 192 | 13 104849 DST MTHFDA 20 MG |
| 193 | 14 104849 DDF MTHFDA CAPSULE |
| 194 | 15 104849 NDC MTHFDA 054868-0511-*2 |
| 195 | Press <RETURN> to see more, '^' to exit this list, OR |
| 196 | CHOOSE 1-15: |
| 197 | 16 104849 NDC RXNORM 58864091730 |
| 198 | 17 104849 TRN MTHFDA PROZAC FLUOXETINE CAPSULES USP |
| 199 | 18 104849 DDF MTHFDA CAPSULE, GELATIN COATED |
| 200 | 19 104849 DRT MTHFDA ORAL |
| 201 | 20 104849 DST MTHFDA 20 MG |
| 202 | Press <RETURN> to see more, '^' to exit this list, OR |
| 203 | CHOOSE 1-20: |
| 204 | 21 104849 DRT MTHFDA ORAL |
| 205 | 22 104849 DRT MTHFDA ORAL |
| 206 | 23 104849 DST MTHFDA 20 MG |
| 207 | 24 104849 DDF MTHFDA CAPSULE, GELATIN COATED |
| 208 | 25 104849 NDC MTHFDA 000077-3105-07 |
| 209 | }}} |
| 210 | |
| 211 | ==== Sources ==== |
| 212 | File 176.004 is the Sources file. It isn't that useful except to check the proprietariness of a source or to check when it was last updated for your database. Here's an example: |
| 213 | |
| 214 | {{{ |
| 215 | OUTPUT FROM WHAT FILE: RXNORM SIMPLE CONCEPT AND ATOM ATTRIBUTES// 176.003 RXNO |
| 216 | RM SOURCE INFORMATION (13 entries) |
| 217 | Select RXNORM SOURCE INFORMATION RSAB: ? |
| 218 | Answer with RXNORM SOURCE INFORMATION RSAB |
| 219 | Do you want the entire 13-Entry RXNORM SOURCE INFORMATION List? y (Yes) |
| 220 | Choose from: |
| 221 | ATC Anatomical Therapeutic Chemical Classification System 3 |
| 222 | GS Gold Standard Drug Database 3 |
| 223 | MDDB Master Drug Data Base 3 |
| 224 | MMSL Multum MediSource Lexicon 1 |
| 225 | MMX Micromedex RED BOOK 3 |
| 226 | MSH Medical Subject Headings, 2013_2013_01_21 0 |
| 227 | MTHFDA Metathesaurus FDA National Drug Code Directory 0 |
| 228 | MTHSPL Metathesaurus FDA Structured Product Labels 0 |
| 229 | NDDF FDB MedKnowledge (formerly NDDF Plus) 3 |
| 230 | NDFRT National Drug File 0 |
| 231 | RXNORM RxNorm Vocabulary 0 |
| 232 | SNOMEDCT_US US Edition of SNOMED CT 9 |
| 233 | VANDF Veterans Health Administration National Drug File 0 |
| 234 | |
| 235 | Select RXNORM SOURCE INFORMATION RSAB: VANDF Veterans Health Administratio |
| 236 | n National Drug File 0 |
| 237 | ANOTHER ONE: |
| 238 | STANDARD CAPTIONED OUTPUT? Yes// (Yes) |
| 239 | Include COMPUTED fields: (N/Y/R/B): NO// - No record number (IEN), no Computed |
| 240 | Fields |
| 241 | |
| 242 | RSAB: VANDF RCUI: C1140288 |
| 243 | VSAB: VANDF_2013_09_27 VCUI: C3530306 |
| 244 | SON: Veterans Health Administration National Drug File |
| 245 | SF: VANDF SVER: 2013_09_27 |
| 246 | IMETA: 2013AA |
| 247 | SLC: Michael Lincoln, M.D.;;U.S. Department of Veterans Affairs, Veterans Heal |
| 248 | th Administration;;;Washington;DC;United States;;;;michael.lincoln@med.va.gov;ht |
| 249 | tp://www.pbm.va.gov/default.aspx |
| 250 | SCC: Michael Lincoln, M.D.;;;;;;;;;;;michael.lincoln@med.va.gov;http://www.pbm |
| 251 | .va.gov/default.aspx SRL: 0 |
| 252 | TTYL: IN,CD,AB,PT,MTH_RXN_CD |
| 253 | ATNL: VAC,DRUG_CLASS_TYPE,VA_CLASS_NAME,DDF,NFI,DCSA,PARENT_CLASS,VMO,SNGL_OR_ |
| 254 | MULT_SRC_PRD,EXCLUDE_DI_CHECK,NDF_TRANSMIT_TO_CMOP,NF_INACTIVATE,VA_DISPENSE_UNI |
| 255 | T,VA_GENERIC_NAME,NF_NAME,NDC LAT: ENG |
| 256 | CENC: UTF-8 CURVER: Y |
| 257 | SABIN: Y SSN: National Drug File |
| 258 | SCIT: ;;;;Veterans Health Administration National Drug File;;;September 27, 20 |
| 259 | 13;Washington, DC;U.S. Department of Veterans Affairs;;;;;;;; |
| 260 | }}} |
| 261 | |
| 262 | According to this, !RxNorm was last updated with VA sources on September 27th 2013. An SRL of 0 means that the source is public domain. |
| 263 | |
| 264 | ==== Relationships ==== |
| 265 | !RxNorm relationships are not easy to query in this version due to Fileman not behaving well with compound B indexes. But they are doable if you know what you are searching for. |
| 266 | |
| 267 | Let's find out the generic drug concept that correspond to the !RxNorm code we obtained via the NDC for Prozac 20mg: |
| 268 | {{{ |
| 269 | Select RXNORM RELATED CONCEPTS RXCUI1: 104849 |
| 270 | RELA: has_tradename |
| 271 | RXCUI2: |
| 272 | |
| 273 | 1 104849 |
| 274 | 2 1048498 |
| 275 | 3 1048499 |
| 276 | CHOOSE 1-3: 1 RXNORM |
| 277 | Select Another RXNORM RELATED CONCEPTS RXCUI1: |
| 278 | RELA: |
| 279 | RXCUI2: |
| 280 | |
| 281 | STANDARD CAPTIONED OUTPUT? Yes// (Yes) |
| 282 | Include COMPUTED fields: (N/Y/R/B): NO// - No record number (IEN), no Computed |
| 283 | Fields |
| 284 | |
| 285 | SAB: RXNORM STYPE1: CUI |
| 286 | REL: RB RXCUI2: 310385 |
| 287 | STYPE2: CUI RELA: has_tradename |
| 288 | RUI: 4086805 RXCUI1: 104849 |
| 289 | SUPPRESS: N CVF: 4096 |
| 290 | }}} |
| 291 | |
| 292 | To confirm that we indeed got the generic, we jump over to 176.001: |
| 293 | {{{ |
| 294 | OUTPUT FROM WHAT FILE: RXNORM RELATED CONCEPTS// 176.001 RXNORM CONCEPT NAMES A |
| 295 | ND SOURCES (687143 entries) |
| 296 | Select RXNORM CONCEPT NAMES AND SOURCES RXCUI: 310385 |
| 297 | 1 310385 RXNORM SCD 310385 Fluoxetine 20 MG Oral Capsul |
| 298 | e |
| 299 | 2 310385 VANDF CD 4008621 FLUOXETINE HCL 20MG CAP |
| 300 | 3 310385 VANDF CD 4013939 FLUOXETINE HCL 20MG CAP,UD |
| 301 | 4 310385 MTHFDA CD 272755 FLUOXETINE / FLUOXETINE HYDRO |
| 302 | CHLORIDE ORAL CAPSULE |
| 303 | 5 310385 MTHFDA CD 235824 FLUOXETINE 20 MG ORAL CAPSULE |
| 304 | }}} |
| 305 | |
| 306 | The Semantic Clinical Drug entry (SCD) for !RxNorm means that we hit the jackpot: That is indeed the canonical generic entry for the branded Prozac 20mg capsule. |